This has been said before but apparently even really smart people aren’t listening. So here’s my top two tips for job applications:

1. Tailor your résumé. If you’re applying for a JavaScript job, highlight the JavaScript experience you have first and foremost. Even something as simple as the order you list skills in makes a difference – if JavaScript is at the end of a list of skills, it’s probably not a priority, if it’s first it makes it seem more important to you, so you seem more qualified.
2. Get a blog, make it look good, fill it with good content.

The corollary to number 2 is that you should set your FaceBook page to private – it never seems to be what you want to have turn up. It’s surprising how many blogs have relatively good technical content but look terrible. Even if you’re not going to be applying for design jobs, having a decent layout without broken images is always helpful.

But really, tailor the résumé – it’s crazy that people don’t do this.